A novel bifunctional multilayered nanofibrous membrane combining polycaprolactone and poly (vinyl alcohol) enriched with platelet lysate for skin wound healing
Andreu Blanquer, Eva Kuželová Košťáková, Elena Filová, Maxim Lisnenko, Antonín Brož, Jana Müllerová, Vít Novotný, Kristýna Havlíčková, Sarka Jakubkova, Šárka HAUZEROVÁ, Bohdana Heczkova, R Procházková, Lucie Bačáková, Věra Jenčová
Abstract
A membrane composed of PCL and PVA layers enriched with platelet lysate was produced to allow cell adhesion and growth and to serve as a drug delivery system that release bioactive compounds in effective concentrations.
Topics & Concepts
Vinyl alcoholPolycaprolactonePlatelet lysateLysisMembraneBifunctionalWound healingAdhesionDrug deliveryMaterials scienceChemistryNanotechnologyOrganic chemistryBiochemistrySurgeryComposite materialIn vitroMedicinePolymerCatalysisElectrospun Nanofibers in Biomedical ApplicationsWound Healing and TreatmentsSilk-based biomaterials and applications