Single-cell analysis highlights a population of Th17-polarized CD4+ naïve T cells showing IL6/JAK3/STAT3 activation in pediatric severe aplastic anemia
Jingliao Zhang, Tianfeng Liu, Yong-Juan Duan, Yanxia Chang, Lixian Chang, Chao Liu, Chao Liu, Xuelian Cheng, Tianyu Li, Wenyu Yang, Xiaojuan Chen, Ye Guo, Yumei Chen, Yao Zou, Li Zhang, Xiaofan Zhu, Yingchi Zhang, Xiaofan Zhu, Yingchi Zhang
Topics & Concepts
Aplastic anemiaImmunologyHaematopoiesisBone marrowImmune systemPopulationHematopoietic stem cell transplantationCD34Peripheral blood mononuclear cellBiologyProinflammatory cytokineStem cellMedicineCancer researchInflammationCell biologyGeneticsIn vitroEnvironmental healthHematopoietic Stem Cell TransplantationImmune Cell Function and InteractionT-cell and B-cell Immunology