TRIM26-mediated degradation of nucleocapsid protein limits porcine reproductive and respiratory syndrome virus-2 infection
Pandeng Zhao, Huiyuan Jing, Dong Wang, Erzhen Duan, Wenting Ke, Ran Tao, Li Yang, Sufang Cao, Haihua Wang, Yan Zhang, Yanting Sun, Jinhe Wang
Topics & Concepts
Porcine reproductive and respiratory syndrome virusBiologyVirologyGene knockdownIRF3RNA interferenceInnate immune systemVirusCoronavirusPlasmidViral replicationImmunityNuclear localization sequenceEctopic expressionImmune systemRNACell cultureGeneImmunologyGeneticsCoronavirus disease 2019 (COVID-19)PathologyDiseaseMedicineInfectious disease (medical specialty)Animal Virus Infections StudiesViral gastroenteritis research and epidemiologyVirus-based gene therapy research