Hyaluronan-Conjugated Carbon Quantum Dots for Bioimaging Use
Bedia Begüm Karakoçak, Amine M. Laradji, Tina Primeau, Mikhail Y. Berezin, Shunqiang Li, Nathan Ravi
Abstract
. Overall, the results show that HA-nCQDs can be used for imaging of CD44-specific tumors in preclinical models of human cancer and potentially used as carriers for targeted drug delivery into CD44-rich cells.
Topics & Concepts
InternalizationCD44Conjugated systemHyaluronic acidMaterials scienceDrug deliveryConjugateCarbodiimideNanotechnologyCancer cellTargeted drug deliveryQuantum dotBiophysicsLigand (biochemistry)ReceptorCancer researchCancerChemistryBiochemistryMedicineBiologyCellAnatomyPolymerMathematicsComposite materialInternal medicineMathematical analysisPolymer chemistryCarbon and Quantum Dots ApplicationsNanocluster Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques