Use of convalescent plasma in hospitalized patients with COVID-19: case series
Livia Hegerova, Ted Gooley, Kelly A. Sweerus, Cynthia L. Maree, Neil A. Bailey, Megumi Bailey, Vanessa Dunleavy, Krish Patel, Kirsten Alcorn, Rebecca Haley, Jill M. Johnsen, Barbara A. Konkle, Annamarie C. Lahti, Morgan L. Alexander, Jason D. Goldman, Anne B. Lipke, Sun-jung Lim, Mark D. Sullivan, John Pauk, John M. Pagel
Abstract
Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.
Topics & Concepts
Convalescent plasmaCoronavirus disease 2019 (COVID-19)MedicineClinical trialSeries (stratigraphy)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicineInternal medicineVirologyOutbreakPaleontologyBiologyDiseaseInfectious disease (medical specialty)COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19COVID-19 Impact on Reproduction