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Pregnancy with COVID‐19: Management considerations for care of severe and critically ill cases

Lian Chen, Hai Jiang, Yangyu Zhao

2020American Journal of Reproductive Immunology26 citationsDOIOpen Access PDF

Abstract

Pregnant women are a potentially highly vulnerable population due to anatomical, physiological, and immunological changes under the COVID-19 pandemic. Issues related to pregnancy with COVID-19 attracted widespread attention from researchers. A large number of articles were published aiming to elaborate clinical characteristics and outcomes of pregnant women infected with COVID-19, in order to provide evidence for management. The existing data suggest that the overall prognosis of pregnancy with COVID-19 is promising when compared with that of other previous coronaviruses. There is still maternal morbidity and mortality related to COVID-19 reported. However, the optimal management of severe and critically ill cases of COVID-19-infected pregnancy is poorly clarified. The possibility of postpartum exacerbation in pregnancy with COVID-19 is also worthy of attention for obstetricians. This review makes further elaboration of the above issues.

Topics & Concepts

PregnancyCoronavirus disease 2019 (COVID-19)ExacerbationMedicinePandemicIntensive care medicineCritically illMaternal morbidityPopulationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakObstetricsImmunologyDiseaseInternal medicineVirologyInfectious disease (medical specialty)Environmental healthBiologyGeneticsOutbreakCOVID-19 Impact on ReproductionMaternal and fetal healthcarePregnancy and preeclampsia studies