Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice
Maria Chen, Boram Kim, Maria Jarvis, Samantha Fleury, Shuyun Deng, Shirin Nouraein, Susan Butler, Sangsin Lee, Courtney Chambers, H. Courtney Hodges, Jerzy O. Szablowski, Junghae Suh, Omid Veiseh
Topics & Concepts
Immune systemAdeno-associated virusGenetic enhancementBiologyGene deliveryVector (molecular biology)ImmunologyViral vectorImmunosuppressionTransduction (biophysics)VirusAntibodyImmunitySystemic administrationVirologyGeneIn vivoGeneticsBiochemistryRecombinant DNAVirus-based gene therapy researchCAR-T cell therapy researchRNA Interference and Gene Delivery