Effect of M0 macrophage-derived exosome miR-181d-5p targeting BCL-2 to regulate NLRP3/caspase-1/GSDMD pathway on human renal mesangial cells pyroptosis
Fu Chai, Xu Chang, Yingliang Lin, Xiaoxia Pang, Shihua Luo, Huatuo Huang, Linxiu Qin, Yan Lan, Yonglong Zeng, Chunfang Wang
Topics & Concepts
PyroptosisMicrovesiclesBiologyFlow cytometryMacrophageWestern blotMesangial cellCell biologyPeripheral blood mononuclear cellMolecular biologyImmunologyInflammationmicroRNAInflammasomeKidneyEndocrinologyGeneIn vitroBiochemistryInflammasome and immune disordersExtracellular vesicles in diseaseOcular Diseases and Behçet’s Syndrome