Dynamic control over feedback regulatory mechanisms improves NADPH flux and xylitol biosynthesis in engineered E. coli
Shuai Li, Zhixia Ye, Eirik A. Moreb, Jennifer N. Hennigan, Daniel Báez Castellanos, Tian Yang, Michael Lynch
Topics & Concepts
XylitolBiochemistryOxidoreductaseFerredoxinFlux (metallurgy)XyloseReductaseMetabolic pathwayPentose phosphate pathwayBiosynthesisThioredoxin reductaseMetabolic engineeringEnzymeChemistryBiologyFermentationGlycolysisThioredoxinOrganic chemistryMicrobial Metabolic Engineering and BioproductionEnzyme Catalysis and ImmobilizationBiofuel production and bioconversion