BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer
Ruoshi Shi, Sebastião N. Martins Filho, Ming Li, Aline Fusco Fares, Jessica Weiss, Nhu‐An Pham, Olga Ludkovski, Vibha Raghavan, Quan Li, D. Ravi, Michael Cabanero, Nadeem Moghal, Natasha B. Leighl, Penelope A. Bradbury, Adrian G. Sacher, Frances A. Shepherd, Kazuhiro Yasufuku, Ming‐Sound Tsao, Geoffrey Liu
Topics & Concepts
AlectinibCrizotinibAnaplastic lymphoma kinaseALK inhibitorMedicineCancer researchLung cancerExome sequencingAdenocarcinomaOncologyMutationInternal medicineCancerBiologyGeneMalignant pleural effusionBiochemistryLung Cancer Treatments and MutationsMelanoma and MAPK PathwaysCancer Mechanisms and Therapy