Discovery of potential epidermal growth factor receptor inhibitors from black pepper for the treatment of lung cancer: an in-silico approach
Olusola Olalekan Elekofehinti, Ifeoluwa Rachael Adetoyi, Hannah Oluwaseun Popoola, Folasade Oluwatobiloba Ayodeji, Foluso Adeola Taiwo, Moses Orimoloye Akinjiyan, Omowunmi Funmilayo Koledoye, Opeyemi Iwaloye, Abayomi Emmanuel Adegboyega
Topics & Concepts
ErlotinibEpidermal growth factor receptorEGFR inhibitorsDocking (animal)Lung cancerKinaseIn silicoPharmacologyTyrosine-kinase inhibitorQuantitative structure–activity relationshipChemistryCancer researchTyrosine kinaseCancerBiologyReceptorBiochemistryMedicineStereochemistryOncologyInternal medicineGeneNursingPiperaceae Chemical and Biological StudiesTraditional and Medicinal Uses of AnnonaceaeComputational Drug Discovery Methods