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Prevalence of anxiety and depression in people with different types of cancer or haematologic malignancies: a cross-sectional study

Elisabeth L. Zeilinger, Claudia Oppenauer, Matthias Knefel, Viktoria Kantor, Carmen Schneckenreiter, Simone Lubowitzki, Katharina Krammer, Chiara Popinger, Anna Kitta, Lea Kum, Feroniki Adamidis, Matthias Unseld, Eva Katharina Masel, Thorsten Füreder, Sabine Zöchbauer‐Müller, Rupert Bartsch, Markus Raderer, Gerald W. Prager, Maria Theresa Krauth, W. R. Sperr, E. Porpaczy, Philipp B. Staber, Peter Valent, Alexander Gaiger

2022Epidemiology and Psychiatric Sciences69 citationsDOIOpen Access PDF

Abstract

AIMS: Cancer patients often present with psychological symptoms that affect their quality of life, physical health outcomes and survival. Two of the most frequent psychiatric comorbidities are anxiety and depression. However, the prevalence of these disorders among cancer patients remains unclear, as studies frequently report varying rates. In the present study, we aimed to provide robust point estimates for the prevalence of anxiety and depression for both a mixed cancer sample and for 13 cancer types separately, considering confounding variables. METHODS: to assess rates of anxiety and depression. Applying ordinal logistic regression models, we compared the prevalence of anxiety and depression between different cancer types, controlling for age and gender. RESULTS: About one third of our sample showed symptoms of anxiety (35.2%) or depression (27.9%), and every sixth patient had a very likely psychiatric condition, with women being more frequently affected. Elderly patients more often showed signs of depression. The prevalence of anxiety and depression was significantly higher in lung and brain cancer patients, than in other cancer patients. Lowest depression rates were found in breast cancer patients. CONCLUSIONS: The prevalence of anxiety and depression is high in cancer patients. Type of cancer is an important predictor for anxiety and depressive symptoms, with lung and brain cancer patients being highly burdened. Considering a personalised medicine approach, physicians should take into account the high prevalence of psychiatric comorbidities and include psychiatric consultations in the treatment plan.

Topics & Concepts

AnxietyDepression (economics)MedicineCancerPsychiatryConfoundingLung cancerBreast cancerHospital Anxiety and Depression ScaleQuality of life (healthcare)Cross-sectional studyInternal medicinePathologyMacroeconomicsNursingEconomicsCancer survivorship and careCancer-related cognitive impairment studiesCancer, Stress, Anesthesia, and Immune Response
Prevalence of anxiety and depression in people with different types of cancer or haematologic malignancies: a cross-sectional study | Litcius