Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts
Wenchang Lv, Shengxuan Liu, Qi Zhang, Zhen Yi, Xiaoyong Bao, Youping Feng, Yuping Ren
Topics & Concepts
KeloidProtein kinase BDownregulation and upregulationFibroblastFibrosisWound healingWestern blotCancer researchPI3K/AKT/mTOR pathwayChemistryApoptosisSignal transductionCell biologyMolecular biologyBiologyPathologyCell cultureMedicineImmunologyBiochemistryGeneGeneticsDermatologic Treatments and ResearchWound Healing and TreatmentsHair Growth and Disorders