Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment
Paula Moyano, José Manuel García, Jimena García, María José Anadón, María Victoria Naval, María Teresa Frejo, Emma Solà, Adela Pelayo, Javier del Pino
Topics & Concepts
Heat shock proteinCholinergicManganeseProgrammed cell deathProteasomeShock (circulatory)ChemistryBiologyInternal medicineCell biologyEndocrinologyBiochemistryMedicineApoptosisGeneOrganic chemistryMitochondrial Function and PathologyEndoplasmic Reticulum Stress and DiseaseTrace Elements in Health