Modulation of the gut microbiota: opportunities and regulatory aspects
Davide G. RIBALDONE, Rinaldo PELLICANO, Sharmila FAGOONEE, Giovanni C. ACTIS
Abstract
The human gut is an intensively colonized organ containing microorganisms that can be health-promoting or pathogenic. This feature led to the development of functional foods aiming to fortify the former category at the expense of the latter. Since long, cultured products, including probiotics fortification, have been used for humans as live microbial feed additions. This review presents some of the microbes used as probiotics and discusses how supplementation with probiotics may help initiate and/or restore eubiotic composition of gut microbiota. Additionally, it considers safety and regulatory aspects of probiotics.
Topics & Concepts
BiologyProbioticGut floraGut microfloraBiotechnologyGut bacteriaFeature (linguistics)Cell biologyComputational biologyHuman healthModulation (music)BacteriaHuman studiesNeuroscienceMicrobiologyRegulatorImmune systemProbiotics and Fermented FoodsGut microbiota and healthMicrobial Metabolites in Food Biotechnology