Litcius/Paper detail

Advancement of Phenoxypyridine as an Active Scaffold for Pesticides

Yanfei Liu, Bin Fu, Yan‐Jun Xu, Bo Ren, Zhaohai Qin

2022Molecules14 citationsDOIOpen Access PDF

Abstract

Phenoxypyridine, the bioisostere of diaryl ethers, has been widely introduced into bioactive molecules as an active scaffold, which has different properties from diaryl ethers. In this paper, the bioactivities, structure-activity relationships, and mechanism of compounds containing phenoxypyridine were summarized, which may help to explore the lead compounds and discover novel pesticides with potential bioactivities.

Topics & Concepts

BioisostereScaffoldChemistryPesticideCombinatorial chemistryMechanism (biology)BiochemistryBiologyChemical synthesisComputer scienceEpistemologyIn vitroDatabasePhilosophyAgronomySynthesis of heterocyclic compoundsSynthesis and Biological EvaluationSynthesis and biological activity