Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer
Xiaoyun Liu, Zitao Guo, Zhendong Chen, Yifan Zhang, Jialan Zhou, Yong Jiang, Qianyu Zhao, Xingxing Diao, Dafang Zhong
Topics & Concepts
CYP3A4IsozymeEnzyme inducerCytochrome P450MicrosomePharmacologyChemistryPharmacokineticsInducerEnzymeBiochemistryBiologyGeneLung Cancer Treatments and MutationsColorectal Cancer Treatments and StudiesHER2/EGFR in Cancer Research