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RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart

Jonathan Heuzé, Samira Kemiha, Antoine Barthe, Alba Torán Vilarrubias, Elyès Aouadi, Umberto Aiello, Domenico Libri, Yea‐Lih Lin, Armelle Lengronne, Jérôme Poli, Philippe Pasero

2023The EMBO Journal23 citationsDOIOpen Access PDF

Topics & Concepts

BiologyRNase PRNase HRNase MRPRNADNA replicationMolecular biologyDNA repairDNACell biologyProliferating cell nuclear antigenGeneticsGeneDNA Repair MechanismsGenomics and Chromatin DynamicsCRISPR and Genetic Engineering
RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart | Litcius