Biocompatible Autonomic Self‐healing PVA‐TA Hydrogel with High Mechanical Strength
Jinxin Huang, Chengwei Wu, Xiaogang Yu, Heng Li, Shuai‐Wen Ding, Wei Zhang
Abstract
Abstract The autonomic self‐healing hydrogel with good biocompatibility is generally poor in tensile strength, which seriously hinders its development and application in the field of loaded biomaterials. Here, based on a large number of strong H bonds formed between poly(vinyl alcohol) (PVA) and tannic acid (TA), an autonomic self‐healing PVA‐TA hydrogel with high strength and high healing efficiency is successfully prepared. The tensile strength of PVA‐TA hydrogel is 224 kPa, which can spontaneously restore to 87% of its initial strength within 2 h after fracture without external stimuli. The obtained hydrogel also shows good biocompatibility.
Topics & Concepts
BiocompatibilityUltimate tensile strengthVinyl alcoholTannic acidSelf-healingMaterials scienceSelf-healing hydrogelsComposite materialMechanical strengthPolymerPolymer chemistryChemistryMedicineOrganic chemistryPathologyMetallurgyAlternative medicineHydrogels: synthesis, properties, applicationsElectrospun Nanofibers in Biomedical ApplicationsPolymer composites and self-healing