Non-replicating vaccinia virus NTV as an effective next-generation smallpox and monkeypox vaccine: evidence from mouse and rhesus monkey models
Qiaohong Chu, Baoying Huang, Mengzhe Li, Xueting Cheng, Shuting Huo, Jiao Ren, Yao Deng, Wenjie Tan
Abstract
The mpox (formerly known as monkeypox) outbreak in May 2022 drew considerable attention towards this disease [1]. Smallpox virus, vaccinia virus (VACV), and monkeypox virus (MPXV) belong to the ort...
Topics & Concepts
MonkeypoxVacciniaVirologySmallpox vaccineSmallpoxOrthopoxvirusBiologyPoxviridaeVirusVaccinationGeneticsRecombinant DNAGenePoxvirus research and outbreaksBacillus and Francisella bacterial researchVirology and Viral Diseases