A portable smartphone-assisted Tb/Eu-MOF agar slice probes for the visual detection of fluoroquinolones
Liwei Cui, Yiqian Zhang, Weifeng Chen, Jingyi Liu, Heli Zhang, Hongshuai Zhu, Jian Zou, Weidan Chang
Abstract
The extensive use of fluoroquinolones (FQs) leads to food residues, which present a significant risk to human health. A portable smartphone-assisted detection platform based on Tb/Eu-MOF nanomaterial was established for the detection of FQs, with the enrofloxacin (ENR) serving as a representative sample. Five Tb/Eu-MOFs with different bimetallic proportions were synthesized, and the Tb/Eu-MOFs (3:1) served as the optimal sensing element. The Tb/Eu-MOF nanomaterial suspension demonstrated a color change from orange-red to pale yellow as a result of fluorescence resonance energy transfer with ENR, attaining a LOD of 0.004 μM and a broad linear range of 0.005-25 μM. The Tb/Eu-MOF was incorporated into an agar slice and coupled with a smartphone for detection to improve portability. A smartphone-based agar slice platform was developed with a linear range of 5-150 μM and a LOD of 4.7 μM. This detection platform offers an innovative, low-cost and portable approach for FQs detection.