Bcl-xL mediates interferon-beta secretion by protease-activated receptor 2 deficiency through the mitochondrial permeability transition pore in colorectal cancer metastasis
Jianhui Ma, Yu Liu, Junhu Yuan, Yiming Ma, Xinhua Zhao, Kun Chen, Xiaoli Zhang, Fanyu Zhang, Hongying Wang
Topics & Concepts
Colorectal cancerMetastasisMitochondrial permeability transition poreChemistryProteaseSecretionCancer researchCancerInternal medicineMedicineApoptosisBiochemistryEnzymeProgrammed cell deathinterferon and immune responsesImmune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative Mechanisms