Efficacy of oral 5 mg melatonin in the treatment of facial melasma in women: A double‐blind, randomized, placebo‐controlled clinical trial
Ingrid Rocha Meireles Holanda, Melissa de Almeida Corrêa Alfredo, Daniel Pinho Cassiano, Ana Cláudia Cavalcante Espósito, Paula Basso Lima, Ediléia Bagatin, Hélio Amante Miot
Abstract
The data that support the findings of this study are available from the corresponding author upon reasonable request. The participants in this manuscript have given written informed consent to the publication of their case details. Ethical approval: This protocol was approved by the FMB-Unesp Institutional Review Board (No. 4.767.182). Trial registration: ReBEC - ensaiosclinicos.gov.br – RBR-10gx2qhj.
Topics & Concepts
MedicineInstitutional review boardMelasmaPlaceboInformed consentClinical trialProtocol (science)Randomized controlled trialDouble blindAlternative medicineFamily medicinePhysical therapyDermatologyInternal medicineSurgeryPathologyDermatologic Treatments and ResearchAcne and Rosacea Treatments and EffectsSkin Protection and Aging