Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
Kate E Findeisen, Julia Sewell, Andrew J.K. Östör
Abstract
Rheumatoid arthritis (RA) is a disease characterised by inflammation of synovial joints and poses a substantial healthcare burden on both the individual and society. One of the most significant shifts in the RA therapeutic landscape has occurred with the introduction of biological disease modifying anti-rheumatic drugs (bDMARDs). There are five classes of bDMARDs currently available, each with a different molecular target and subtle differences in their efficacy and safety profile. This review also describes the "real-world" use of bDMARDs and how they fit into the overall RA treatment guidelines.
Topics & Concepts
Rheumatoid arthritisMedicineIntensive care medicinePhysical therapyInternal medicineRheumatoid Arthritis Research and TherapiesBiosimilars and Bioanalytical MethodsMonoclonal and Polyclonal Antibodies Research