N-trimethyl chitosan coated nano-complexes enhance the oral bioavailability and chemotherapeutic effects of gemcitabine
Guanyu Chen, Darren Svirskis, Weiyue Lu, Ying Man, Hongyu Li, Min Liu, Jingyuan Wen
Topics & Concepts
BioavailabilityChitosanChemistryPharmacologyPLGAPharmacokineticsPoloxamerDrugPolyethylene glycolPolymerBiochemistryOrganic chemistryMedicineIn vitroCopolymerNanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsDrug Solubulity and Delivery Systems