Electrochemically driven α-thiocarbamylation <i>via</i> a dehydrocoupling strategy of β-ketoesters with amines and CS<sub>2</sub>
Qian Wang, Xiu‐Jin Meng, Haitao Tang, Ying‐Ming Pan, Wengui Duan, Mu‐Xue He
Abstract
We disclose a feasible strategy for the electrochemical dehydrogenative coupling of CS 2 and amines with β-ketoesters, which leads to dithiocarbamate intermediates in the presence of bases.
Topics & Concepts
DithiocarbamateElectrochemistryChemistryCombinatorial chemistryOrganic chemistryElectrodePhysical chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions