Comparison of First and Second Wave Cohorts of Multisystem Inflammatory Disease Syndrome IN Children
Ashraf S. Harahsheh, Matthew P. Sharron, James E. Bost, Emily Ansusinha, David Wessel, Roberta L. DeBiasi
Abstract
Comparing first and second wave MIS-C cohorts at our quaternary pediatric institution, second wave were older, presented more frequently with shortness of breath, higher maximum troponin and N-terminal BNP, and more frequently required advanced respiratory and inotropic support. Despite increased severity in the second cohort, both cohorts had similar rates of coronary artery abnormalities, systolic dysfunction, and length of stay.
Topics & Concepts
MedicineInternal medicineCardiologyCoronary artery diseaseCohortTroponinInotropeDiseasePediatricsRespiratory systemCohort studyRespiratory diseaseMultisystem diseaseElectrocardiographyRetrospective cohort studyAcute coronary syndromeBlood pressureSeverity of illnessArterial diseaseKawasaki Disease and Coronary ComplicationsInflammasome and immune disordersCOVID-19 Impact on Reproduction