A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m6A -dependent activation of multiple oncogenes
Yingxiu Luo, Mengjia He, Jie Yang, Feifei Zhang, Jie Chen, Xuyang Wen, Jiayan Fan, Xianqun Fan, Peiwei Chai, Renbing Jia
Topics & Concepts
RetinoblastomaCancer researchRetinoblastoma proteinDownregulation and upregulationBiologyCell growthCellCell cycleGeneGeneticsRNA modifications and cancerinterferon and immune responsesCancer-related molecular mechanisms research