Rapid identification of human mast cell degranulation regulators using functional genomics coupled to high-resolution confocal microscopy
Jelle Folkerts, Nicolas Gaudenzio, Marcus Maurer, Rudi W. Hendriks, Ralph Stadhouders, See‐Ying Tam, Stephen J. Galli
Topics & Concepts
DegranulationFunctional genomicsCRISPRBiologyMast cellGene knockdownSmall hairpin RNACell biologyRNA interferenceTransfectionSingle-cell analysisGenome editingComputational biologyConfocal microscopyGene expression profilingCellCell cultureGene expressionGeneGenomicsRNAGeneticsGenomeImmunologyReceptorCRISPR and Genetic EngineeringRNA regulation and diseaseRetinal Development and Disorders