Litcius/Paper detail

High GABA-producing <i>Lactococcus lactis</i> ZFM559 and its derived GABA alleviate chronic unpredictable mild stress (CUMS)-induced depression <i>via</i> the “microbiota–brain” axis

Jiarun Han, Shi Hu, Xilian Zhao, Lina Ding, Jiaqi Yin, Jiaqi Liu, Ping Li, Qing Gu

2025Food & Function7 citationsDOI

Abstract

γ-Aminobutyric acid (GABA) is a crucial inhibitory neurotransmitter with recognized benefits in alleviating depression.

Topics & Concepts

Lactococcus lactisGut–brain axisDepression (economics)Chronic stressNeuroscienceGlutamate receptorChemistryBiologyPharmacologyBacteriaBiochemistryReceptorGut floraGeneticsLactic acidEconomicsMacroeconomicsGABA and Rice ResearchTryptophan and brain disordersBiochemical effects in animals