Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains
Momoka Iiyama, Nobutaka Numoto, Shuhei Ogawa, Masataka Kuroda, Hisayuki Morii, Ryo Abe, Nobutoshi Ito, Masayuki Oda
Topics & Concepts
SH2 domainCD28PhosphopeptideT-cell receptorMutantMolecular biologyBiologyT cellCell biologyBinding siteCytoplasmProtein subunitChemistrySignal transductionKinaseBiochemistryTyrosine kinaseGeneticsImmune systemGeneT-cell and B-cell Immunologyvaccines and immunoinformatics approachesNF-κB Signaling Pathways