Alcohol drinking during early adolescence activates microglial cells and increases frontolimbic Interleukin-1 beta and Toll-like receptor 4 gene expression, with heightened sensitivity in male rats compared to females
Andrea Silva-Gotay, Jillian Davis, Elizabeth R. Tavares, Heather N. Richardson
Topics & Concepts
Prefrontal cortexMicrogliaEndocrinologyInternal medicineBinge drinkingHippocampusReceptorAlcoholInflammationTLR4PsychologyMedicineNeuroscienceBiologyCognitionAlcohol consumptionBiochemistryNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersStress Responses and Cortisol