Immune checkpoint inhibitor-related thyroid dysfunction
F. Illouz, Claire Briet, Patrice Rodien
Abstract
Immune checkpoint inhibitors (ICIs) are currently the key therapy for several cancers. Among immune-related adverse events, thyroid dysfunction is the most frequent. We review this thyroid dysfunction, with recent data on epidemiology, diagnostic considerations, management and risk factors.
Topics & Concepts
Thyroid dysfunctionMedicineImmune DysfunctionAdverse effectImmune systemThyroidImmunologyInternal medicineCancer Immunotherapy and BiomarkersNeuroendocrine Tumor Research AdvancesLung Cancer Treatments and Mutations