Phage-delivered sensitisation with subsequent antibiotic treatment reveals sustained effect against antimicrobial resistant bacteria
Hongbo Liu, Hao Li, Yuan Liang, Xinying Du, Chaojie Yang, Lang Yang, Jing Xie, Rongtao Zhao, Yigang Tong, Shaofu Qiu, Hongbin Song
Abstract
: The PRESA strategy for eradicating resistant bacteria showed high bactericidal efficacy and a sustained inhibition effect against resistant bacteria. By restoring the efficacy of low-cost antibiotics, PRESA could be developed as an efficient and economical therapy for infections of antibiotic resistant bacteria.
Topics & Concepts
AntimicrobialAntibioticsBacteriaMicrobiologyAntibiotic resistanceChemistryBiologyMedicineGeneticsBacteriophages and microbial interactionsAntibiotic Resistance in BacteriaCRISPR and Genetic Engineering