Litcius/Paper detail

Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors

Shifali Shishodia, Marina Demetriades, Dong Zhang, Nok Yin Tam, Pratheesh Maheswaran, Caitlin Clunie‐O'Connor, Anthony Tumber, Ivanhoe K. H. Leung, Yi Min Ng, T.M. Leissing, Afaf H. El‐Sagheer, E. Salah, Tom Brown, Wei Shen Aik, M.A. McDonough, Christopher J. Schofield

2021Journal of Medicinal Chemistry22 citationsDOIOpen Access PDF

Abstract

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Topics & Concepts

ChemistryAlkBEnzymeDemethylationIn vivoBromodomainOxygenaseStereochemistryBiochemistryHistoneGeneGene expressionBiologyDNA methylationGeneticsDNA repairRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation