Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors
Shifali Shishodia, Marina Demetriades, Dong Zhang, Nok Yin Tam, Pratheesh Maheswaran, Caitlin Clunie‐O'Connor, Anthony Tumber, Ivanhoe K. H. Leung, Yi Min Ng, T.M. Leissing, Afaf H. El‐Sagheer, E. Salah, Tom Brown, Wei Shen Aik, M.A. McDonough, Christopher J. Schofield
Abstract
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Topics & Concepts
ChemistryAlkBEnzymeDemethylationIn vivoBromodomainOxygenaseStereochemistryBiochemistryHistoneGeneGene expressionBiologyDNA methylationGeneticsDNA repairRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation