Litcius/Paper detail

Synthetic half-reactions

Andrei K. Yudin

2020Chemical Science10 citationsDOIOpen Access PDF

Abstract

This perspective on reactivity introduces Synthetic Half-Reactions (SHRs) as a way to analyze chemical transformations. SHRs denote either an uphill transformation leading to a higher energy state or a downhill transformation leading to a lower energy state. Using well-established processes, I show how the matching of different classes of SHRs offers a tool to classify chemical transformations. This raises the possibility to discover new processes by finding underappreciated combinations of endergonic and exergonic steps.

Topics & Concepts

Reactivity (psychology)Perspective (graphical)Combinatorial chemistryChemistryChemical reactionBiochemical engineeringComputational chemistryComputer scienceOrganic chemistryEngineeringArtificial intelligenceMedicinePathologyAlternative medicineChemical Synthesis and AnalysisClick Chemistry and ApplicationsChemical Synthesis and Reactions