Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
Malik Galijašević, Ruth Steiger, Stephanie Mangesius, Julian Mangesius, Johannes Kerschbaumer, Christian F. Freyschlag, Nadja Gruber, Tanja Janjic, Elke R. Gizewski, Astrid Grams
Abstract
Preoperative grade prediction is important in diagnostics of glioma. Even more important can be follow-up after chemotherapy and radiotherapy of high grade gliomas. In this review we provide an overview of MR-spectroscopy (MRS), technical aspects, and different clinical scenarios in the diagnostics and follow-up of gliomas in pediatric and adult populations. Furthermore, we provide a recap of the current research utility and possible future strategies regarding proton- and phosphorous-MRS in glioma research.
Topics & Concepts
GliomaProton magnetic resonanceMedicineMagnetic resonance imagingRadiation therapyMedical physicsIn vivo magnetic resonance spectroscopyRadiologyNuclear magnetic resonanceCancer researchPhysicsGlioma Diagnosis and TreatmentAdvanced MRI Techniques and ApplicationsMedical Imaging Techniques and Applications