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The role of water molecules in the dissociation of an electron-molecule contact pair

Connor J. Clarke, E. Michi Burrow, Jan R. R. Verlet

2025Nature Communications10 citationsDOIOpen Access PDF

Abstract

Abstract The hydrated electron, e – (aq) , is a potent reducing agent and a prototypical quantum solute. Reactions of e – (aq) often involve a contact pair comprised of a molecule and electron that are hydrated within a single sphere. However, a molecular-level understanding of the solvent-driven coordinate that links the contact pair to the free dissociated e – (aq) remains elusive. Here, we study this coordinate by kinetically trapping representative metastable intermediates as gas-phase clusters and probing them using photoelectron spectroscopy. We apply this methodology to uracil-water anion clusters, where key intermediates are identified with supporting quantum chemical calculations. Just a single water molecule drives the parent molecule and non-valence electron apart, thereby inhibiting geminate recombination to form the more stable valence-bound uracil anion. The electron-water binding is akin to bare water cluster anions, highlighting the link to larger clusters and e – (aq) . Our results provide a molecular-level view of quantum solute hydration and, more broadly, of how water-driven electron-transfer reactions proceed.

Topics & Concepts

MoleculeDissociation (chemistry)ChemistryMetastabilityChemical physicsWater clusterElectron transferIonSolvated electronElectronValence (chemistry)Valence electronX-ray photoelectron spectroscopyPhotochemistryPhysical chemistryHydrogen bondPhysicsRadiolysisAqueous solutionNuclear magnetic resonanceOrganic chemistryQuantum mechanicsAdvanced Chemical Physics StudiesPhotochemistry and Electron Transfer StudiesInorganic Fluorides and Related Compounds
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