Transition Metal‐Catalyzed Dual C−H Activation/Annulation Reactions Involving Internal Alkynes
Fatemeh Doraghi, Mohammad Sadegh Karimtabar, Mehran Ghasemi, Bagher Larijani, Mohammad Mahdavi
Abstract
Recently, transition metal-catalyzed ortho-C-H bond activation/annulations involving two internal alkyne molecules have been extensively used to synthesize highly substituted polycyclic aromatic scaffolds. Such reactions have emerged as a powerful atom and step-economical strategy for the assembly of multifunctional bioactive molecules. In this context, we focused on the recent achievements of dual C-H bond activation/annulations, as well as functionalization reactions involving diaryl/alkyl alkynes.
Topics & Concepts
AnnulationAlkyneCatalysisChemistryContext (archaeology)AlkylTransition metalCombinatorial chemistryMoleculeDual roleDual (grammatical number)StereochemistryOrganic chemistryBiologyPaleontologyArtLiteratureCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCyclopropane Reaction Mechanisms