Electrochemically enabled synthesis of multi-substituted pyrazoles <i>via</i> a radical cyclization cascade
Wan‐Jie Wei, Y. M. Zeng, Xianfeng Liang, Fei‐Hu Cui, Maorui Wang, Ying‐Ming Pan, Wengui Duan, Haitao Tang
Abstract
We have developed a mild and efficient electrochemical reduction approach employing aryl diazonium salts as dual synthons to synthesize valuable multi-substituted pyrazoles for the first time.
Topics & Concepts
CascadeChemistryCombinatorial chemistryRadical cyclizationOrganic chemistryChromatographyRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods