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Single-cell RNA sequencing reveals the sustained immune cell dysfunction in the pathogenesis of sepsis secondary to bacterial pneumonia

Teng Wang, Xianglong Zhang, Zhanguo Liu, Yao Tong, Dongying Zheng, Jianwei Gan, Shuang Yu, Lin Li, Peng Chen, Jian Sun

2021Genomics91 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemSepsisImmunologyBiologyPathogenesisPneumoniaPeripheral blood mononuclear cellDownregulation and upregulationInterferonCellMedicineGeneIn vitroInternal medicineBiochemistryGeneticsImmune Cell Function and InteractionNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancer