Litcius/Paper detail

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

Markus Hoffmann, Hannah Kleine‐Weber, Stefan Pöhlmann

2020Molecular Cell2,072 citationsDOIOpen Access PDF

Topics & Concepts

FurinBiologyCleavage (geology)CoronavirusVirologyProteaseVirulenceCellVirusCell biologyGeneticsCoronavirus disease 2019 (COVID-19)EnzymeBiochemistryGeneDiseasePathologyMedicinePaleontologyInfectious disease (medical specialty)Fracture (geology)SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesVirus-based gene therapy research