The elevated level of IL-1α in the bone marrow of aged mice leads to MSC senescence partly by down-regulating Bmi-1
Xueling Zheng, Qianxing Wang, Zhuo Xie, Jiao Li
Topics & Concepts
SenescenceMesenchymal stem cellBone marrowOsteoporosisPhenotypeEndocrinologyInternal medicineOsteoblastMedicineStem cellBiologyCancer researchCell biologyIn vitroGeneticsGeneTelomeres, Telomerase, and SenescenceMesenchymal stem cell researchNF-κB Signaling Pathways