A novel peptide design aids in the expression and its simplified process of manufacturing of Insulin Glargine in Pichia pastoris
Partha Hazra, Suma Sreenivas, Krishnamurthy Venkatesan, Mukesh B. Patale, Amarnath Chatterjee, N. Ramprabu, Ajamoddin M. Shaikh, Mutyalasetty Kusumanchi
Topics & Concepts
Pichia pastorisPeptideTrypsinChemistryC-peptideInsulinInsulin glargineEnzymeCombinatorial chemistryCleavage (geology)BiochemistryRecombinant DNABiologyFracture (geology)EndocrinologyGenePaleontologyHypoglycemiaProtein purification and stabilityMonoclonal and Polyclonal Antibodies ResearchReceptor Mechanisms and Signaling