Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
Martin Golkowski, Ho-Tak Lau, Marina Chan, Heidi L. Kenerson, Venkata Narayana Vidadala, Anna Shoemaker, Dustin J. Maly, Raymond S. Yeung, Taranjit S. Gujral, Shao‐En Ong
Topics & Concepts
KinomeDruggabilityHepatocellular carcinomaEpithelial–mesenchymal transitionCancer researchDrug resistanceKinaseSorafenibDrugSignal transductionMedicineBiologyBioinformaticsCancerPharmacologyInternal medicineGeneMetastasisGeneticsCancer Mechanisms and TherapyUbiquitin and proteasome pathwaysFOXO transcription factor regulation