Intranasal delivery of Borneol/R8dGR peptide modified PLGA nanoparticles co-loaded with curcumin and cisplatin alleviate hypoxia in pediatric brainstem glioma which improves the synergistic therapy
Xiao Guang Zhao, Shuting Ni, Yangjie Song, Kaili Hu
Topics & Concepts
Nasal administrationPharmacologyCurcuminBorneolChemistryCisplatinGliomaHypoxia (environmental)AngiogenesisBlood–brain barrierSystemic administrationPLGACancer researchMedicinePathologyChemotherapyIn vivoBiochemistryCentral nervous systemInternal medicineBiologyIn vitroTraditional Chinese medicineOxygenBiotechnologyOrganic chemistryAlternative medicineRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics