Carbene-catalyzed activation of cyclopropylcarbaldehydes for mannich reaction and δ-lactam formation: remote enantioselecitvity control and dynamic kinetic asymmetric transformation
Jie Lv, Jun Xu, Xuling Pan, Zhichao Jin, Yonggui Robin
Topics & Concepts
Enantioselective synthesisCarbeneLactamChemistryMannich reactionCatalysisCombinatorial chemistryTransformation (genetics)Kinetic energyOrganic chemistryPhysicsGeneQuantum mechanicsBiochemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCyclopropane Reaction MechanismsSynthetic Organic Chemistry Methods