Tumor-infiltrating CD8+ T cells in ALK-positive lung cancer are functionally impaired despite the absence of PD-L1 on tumor cells
Chenxi Zeng, Yi Gao, Jing Xiong, Jiawei Lu, Jianjian Yang, Xue Wang, Yixin Cai, Lequn Li, Xiangning Fu
Topics & Concepts
Anaplastic lymphoma kinaseCancer researchCD8PD-L1MedicineImmunotherapyTumor microenvironmentCytotoxic T cellLung cancerEpidermal growth factor receptorAnaplastic large-cell lymphomaCD30Immune systemLymphomaCancerImmunologyPathologyBiologyInternal medicineIn vitroMalignant pleural effusionBiochemistryCancer Immunotherapy and BiomarkersLung Cancer Treatments and MutationsLung Cancer Research Studies