Antiepileptic Drugs and Bone Health: Current Concepts
Antonio Siniscalchi, Séan Murphy, Erika Cione, Leonardo Piro, Giovambattista De Sarro, Luca Gallelli
Abstract
Chronic use of antiepileptic drugs (AEDs) can induce the development of adverse effects on bone metabolism. In epileptic patients treated with AED, the monitoring of biochemical markers of bone turnover, such as the measurement of serum 25 (OH) vitamin D, bone mineral density, before the beginning of the treatment and during the follow-up is not routinely required. In the future, monitoring of biochemical markers in epileptic patients treated with AED may help us for adequate prevention therapy.
Topics & Concepts
MedicineBone remodelingEpilepsyBone healthAdverse effectVitamin D and neurologyIntensive care medicineBone mineralPharmacologyOsteoporosisInternal medicinePsychiatryPharmacological Effects and Toxicity StudiesEpilepsy research and treatmentBone and Joint Diseases