Litcius/Paper detail

Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer

Xiaoxiang Sun, Huanyin Tang, Yu Chen, Zhixi Chen, Zhiyi Hu, Zhen Cui, Yaming Tao, Jian Yuan, Yun Fu, Zhigang Zhuang, Qizhi He, Qian Li, Xianghong Xu, Xiaoping Wan, Ying Jiang, Zhiyong Mao

2023Nature Cancer62 citationsDOI

Topics & Concepts

PARP1Cancer researchDeubiquitinating enzymeTriple-negative breast cancerBiologyEstrogen receptorReceptorPoly ADP ribose polymeraseBreast cancerCancerUbiquitinPolymeraseBiochemistryEnzymeGeneticsGenePARP inhibition in cancer therapyDNA Repair MechanismsCell death mechanisms and regulation
Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer | Litcius